Recent studies of laboratory animals provide further support that cognitive function and physical performance are enhanced by IF. Summary of the major metabolic pathways involved in the metabolic switch and responses of excitable cells to the ketone β-hydroxybutyrate (β-OHB). AcAc, acetoacetate; ATP, adenosine triphosphate; FFA, free fatty acids; TCA, tricarboxylic acid. Future research will need to explore whether combining time-restricted eating with reduced calorie intake produces stronger benefits.
Health Conditions
- It’s part of many religious practices and plays a role in a lot of human cultures.
- Alterations of insulin concentrations triggered by lower energy intake during Ramadan may therefore lead to shifts in leptin concentrations.
- A major factor seems to be lipid-induced mitochondrial stress, which is the main site of endogenous reactive oxygen species production.
- This doesn’t happen after one meal; it happens when you’re running at a caloric deficit for a long period of time.
- Instead, shrinking that window and shifting calorie consumption to the daytime can put your feeding more in line with circadian rhythms.
- Indeed, during fasting, human skeletal muscle relies on lipid oxidation, potentially triggering the development of insulin resistance and impaired glucose uptake.
It was shown that excluding each individual study has no effect on the overall results of FBS, BS, and HOMA-IR. In contrast, the studies by Manoogian et al. (16), Suthutvoravut et al. (17), and Cramer et al. (18) have the potential to alter the levels of HbA1c to a non-significant form. Additionally, sensitivity analyses showed that the exclusion of Manoogian et al. (16), Cramer et al. (18), Guo et al. (19), and Li et al. (20) altered the pooled results for insulin levels. In addition, sensitivity analyses of lipid markers demonstrated that excluding the study by He et al. (21) could affect the overall results of TC. Similarly, excluding Sun et al.(22), Manoogian et al. (16) were able to significantly alter the effect of fasting on TG levels. Nonetheless, the leave-one-out approach had no significant effect on LDL-C and HDL-C outcomes.
Dato-DXd Receives Priority Review in Unresectable/Metastatic TNBC
My favorite way to break a fast is with some broth or chicken soup. Our daily routines are really linked to hunger signals, so it’s a good idea to change things up, especially early in your fasting practice. If you are prone to hypoglycemia or if your diet is very high in sugar or starch going into the fast, that can cause some blood sugar issues. While you might experience some symptoms of low blood sugar — like shakiness or feeling ‘hangry’ — those usually only happen when you first start incorporating fasting into your lifestyle.
Which intermittent fasting schedule should I follow?
This is a weight loss technique that focuses on when you can eat instead of what you can eat. Studies have shown that IF is just as effective as traditional calorie-cutting methods in terms of the amount of weight you’ll lose. When you fast, you stop consuming calories for an extended period of time.
Tips For Not Gaining Weight After A Fast
This makes IF a more promising method for sustainable weight loss as most traditional diets result in weight regain of at least the amount of weight originally lost, if not more. Over the next few hours, the body completes the breakdown of carbs into glucose. Blood sugar levels start to drop as the glucose from the food eaten is now mostly used or stored. The duration of the fasting time varies from person to person but is usually between 12 and 16 hours2. This tends to be the easiest and most repetitive method of IF to follow. In our modern world, a growing number of individuals grapple with metabolic health issues, often feeling trapped in a cycle of fluctuating energy levels, weight gain, and overall decreased vitality.
Impact of Intermittent Fasting on Changes in Body Composition in Humans
IF may also help lower your risk of developing type II diabetes and heart disease. Triple-negative breast cancer (TNBC) is a challenging subtype to treat due to its aggressive nature and lack of targeted hormonal receptors. However, emerging research suggests that the metabolic landscape of TNBC may be its “Achilles’ heel.”
powerful benefits of the anti-inflammatory diet (and where Lumen fits in)
Responsible fasting allows your body unimeal reviews complaints to utilize stored energy from fat deposits and activate autophagy to rejuvenate cells. By combining fasting with strength training and exercise, you can lose unwanted fat stores while preserving muscle. Intermittent fasting is popular with people who find it helpful for managing appetite, weight, and overall well-being.
Time-restricted eating and fasting
For many people with a history of eating disorders, fasting is not going to be a good fit. This measures the amount of energy your body burns to keep all your organs functioning optimally. If you’re having symptoms of irregular blood sugar levels, some green tea with cinnamon is a useful aid as cinnamon can help regulate blood sugar. Studies of prolonged fasts have found no evidence of electrolyte imbalances in the blood, however, salt is still a great tool to reduce hunger. Fasting of 72+ hours is also shown to improve the body’s response to toxin exposure and stress hormones.

But other research suggests that eating breakfast isn’t such a great weight loss strategy. GH is known to upregulate hepatic glucose output, leading to positive nitrogen balance, and lipolysis31). Thus, GH might be a key factor to maintain protein during fasting. Interestingly, the effects of GH on lipolysis seem to be enhanced in the fasting state as compared to the fed state. On the other hand, fasting leads to decreased insulin sensitivity and IGF-I bioactivity in response to GH administration during fasting32).
I encourage you to start experimenting so you can enjoy the myriad of benefits it can create. And if you want help creating the most effective and safest protocol for you and your health, click here to work with me. Food is culture, it’s family, it’s celebration — and fasting allows you to participate in all of those parts of life without anxiety and food guilt.
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When is the best time to fast?
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How Is Intermittent Fasting Connected to Metabolic Health?
While intermittent fasting (IF) seemed to initially gain popularity as a weight loss method, research is showing that the potential benefits go well beyond weight management1. This article will explore the mechanisms by which IF works and some benefits and potential risks of practicing this eating style. There are many reasons some individuals /unimeal experience difficulties adhering to IF regimens, but most notably is the fact that very few studies ensured that “the switch” was truly flipped and ketosis was achieved.
This test requires only a single blood sample and provides an objective snapshot of a person’s internal timing. The ChronoFast study used this method and confirmed that eating schedules can shift internal clocks in humans. If you’ve been doing a multi-day fast, it will usually take about half the number of days you fasted for your digestive system to return to normal. I would avoid raw food in general, as that can be harder to digest.
